• Fct: FUNCTIONALITY
• F: Functional
• P: Pseudogene
• ORF: Open Reading Frame
• R: Rearranged
• T: Transcribed
• Pr: Translated into protein

"+" or "-" indicates if the gene sequences have been found (+) or not been found (-) rearranged (R), transcribed (T), and/or translated into protein (Pr). Arbitrarily that information is shown on the first line of each gene when the data have been confirmed by several studies.

Functionality is shown between parentheses, (F) and (P), when the accession number refers to a cDNA sequence and the corresponding genomic gene has not yet been isolated.

For a given gene name, each horizontal line corresponds to a different allele. For more information, see Alignments of alleles and Tables of alleles (IMGT Repertoire).

Click on an accession number to get the sequence and additional information (IMGT annotations, IMGT flat file, Coding regions...).

IGHV subgroup	IGHV gene name	Fct	R	T	Pr	Reference sequences	Accession numbers	Sequences from the literature
IGHV1	IGHV1S1	F				V1b	Z49188 [1]
	IGHV1S2	F				Vg1u	Z49180 [1]
	IGHV1S3	F				Vge6u	Z49182 [1]
	IGHV1S4	F				V7a	Z49186 [1]
	IGHV1S5	F				V5a	Z49187 [1]
	IGHV1S6	F				Vge7u	Z49181 [1]
	IGHV1S7	(F)	+	+			AJ505121 [2] #c
	IGHV1S8	P (1)				Vg5u	Z49183 [1]
	IGHV1S9	P (2)				Vg2u	Z49184 [1]
	IGHV1S10	P (3)				Vg10u	Z49185 [1]

#c: rearranged cDNA.

IMGT notes:

(1)	No INIT-CODON (CAA instead of ATG) and a DELETION of 11 nucleotides at position 9 in L-PART1, and no CONSERVED_TRP.
(2)	DELETION of 11 nucleotides at position 9 in L-PART1, and no CONSERVED_TRP.
(3)	DELETION of 11 nucleotides at position 9 in L-PART1,and no CONSERVED_TRP.

References:

[1]	Dufour, V. et al., J. Immunol., 156, 2163-2170 (1996).
[2]	Ladeveze, V. and Nau, F., Unpublished.

Created: 13/11/2002
Author: Delphine Guiraudou
Contact: Marie-Paule Lefranc

Software material and data coming from IMGT server may be used for academic research only, provided that it is referred to IMGT®, and cited as "IMGT®, the international ImMunoGeneTics information system® http://www.imgt.org (founder and director: Marie-Paule Lefranc, Montpellier, France)." References to cite: Lefranc, M.-P. et al., Nucleic Acids Research, 27, 209-212 (1999) Cover of NAR; Ruiz, M. et al., Nucleic Acids Research, 28, 219-221 (2000); Lefranc, M.-P., Nucleic Acids Research, 29, 207-209 (2001); Lefranc, M.-P., Nucleic Acids Res., 31, 307-310 (2003); Lefranc, M.-P. et al., In Silico Biol., 5, 0006 (2004) [Epub], 5, 45-60 (2005); Lefranc, M.-P. et al., Nucleic Acids Res., 33, D593-D597 (2005) Full text; Lefranc, M.-P. et al., Nucleic Acids Research 2009 37: D1006-D1012; doi:10.1093/nar/gkn838 Full text.

For any other use please contact Marie-Paule Lefranc Marie-Paule.Lefranc@igh.cnrs.fr.

IMGT Repertoire (IG and TR)
IMGT Repertoire (MHC)
IMGT Repertoire (RPI)
IMGT Index
IMGT Scientific chart
IMGT Education
IMGT Home page

IMGT founder and director: Marie-Paule Lefranc Marie-Paule.Lefranc@igh.cnrs.fr Bioinformatics manager: Véronique Giudicelli Veronique.Giudicelli@igh.cnrs.fr Computer manager: Patrice Duroux Patrice.Duroux@igh.cnrs.fr Webmaster: Chantal Ginestoux Chantal.Ginestoux@igh.cnrs.fr
Citing IMGT Warranty disclaimer and copyright notice Privacy policy and advertisement policy © Copyright 1995-2010 IMGT®, the international ImMunoGeneTics information system®