IMGT Web resources

IMGT Repertoire (IG and TR)

IMGT Repertoire comprises LIGM expertized data on immunoglobulins (IG), T cell receptors (TR) and major histocompatibility complex (MHC) and related proteins of the immune system.

1. Locus and genes

• Chromosomal localizations
• Locus representations
• Locus description
• Gene positions
• Gene exon/intron organization
• Gene exon/intron splicing sites
• Gene tables
• Potential germline repertoires
• Lists of human IG and TR genes, groups, loci and orphons
• Lists of Mouse (Mus musculus) IG and TR genes, groups and loci
• Clans
• Correspondence between nomenclatures
• Correspondence between species

2. Proteins and alleles

• Protein displays
• Alignments of alleles
• Tables of alleles
• Allotypes
• Isotypes
• Particularities in protein designations
• IMGT reference directory in FASTA format
• Correspondence between IG and TR chain, gene and receptor IMGT designations

3. 2D and 3D structures

• Colliers de Perles
• Colliers de Perles with hydrogen bonds
• 3D representations
• FR-IMGT and CDR-IMGT lengths (V-REGION and V-DOMAIN)
• CDR-IMGT 3D structures
• Strand and loop lengths (C-DOMAIN)
• Examples of C-DOMAINs
• Proteins with known 3D structures

4. Probes and RFLP

• Phages
• Probes
• RFLP alleles and frequencies
• Polymorphisms by insertion/deletion
• Rearrangements

5. Taxonomy

• IMGT Taxonomy tree
• List of the Latin and English names of the species in IMGT/LIGM-DB
• List of the mouse strains in IMGT Repertoire
• Non-vertebrates in IMGT/LIGM-DB

6. Gene regulation and expression

• Promoters
• cDNAs
• Reagents monoclonal antibodies

7. Genes and clinical entities

• Translocations and inversions
• Humanized antibodies
• Monoclonal antibodies with clinical indications

Created: 18/04/1997
Last updated: Friday, 15-Jan-2010 17:12:50 CET
Editors: Chantal Ginestoux, Géraldine Folch
Contact: Marie-Paule Lefranc

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Software material and data coming from IMGT server may be used for academic research only, provided that it is referred to IMGT®, and cited as "IMGT®, the international ImMunoGeneTics information system® http://www.imgt.org (founder and director: Marie-Paule Lefranc, Montpellier, France)." References to cite: Lefranc, M.-P. et al., Nucleic Acids Research, 27, 209-212 (1999) Cover of NAR; Ruiz, M. et al., Nucleic Acids Research, 28, 219-221 (2000); Lefranc, M.-P., Nucleic Acids Research, 29, 207-209 (2001); Lefranc, M.-P., Nucleic Acids Res., 31, 307-310 (2003); Lefranc, M.-P. et al., In Silico Biol., 5, 0006 (2004) [Epub], 5, 45-60 (2005); Lefranc, M.-P. et al., Nucleic Acids Res., 33, D593-D597 (2005) Full text; Lefranc, M.-P. et al., Nucleic Acids Research 2009 37: D1006-D1012; doi:10.1093/nar/gkn838 Full text.
For any other use please contact Marie-Paule Lefranc Marie-Paule.Lefranc@igh.cnrs.fr.

     

IMGT founder and director: Marie-Paule Lefranc Marie-Paule.Lefranc@igh.cnrs.fr
Bioinformatics manager: Véronique Giudicelli Veronique.Giudicelli@igh.cnrs.fr
Computer manager: Patrice Duroux Patrice.Duroux@igh.cnrs.fr
Webmaster: Chantal Ginestoux Chantal.Ginestoux@igh.cnrs.fr

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